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up to 2 uM
1 H NMR (600 MHz, DMSO-d6) δ ppm: 10.54 (s, 1H), 8.92 (s, 1H), 8.56 (d, J = 2.3 Hz, 1H), 8.50 (d, J = 2.3 Hz, 1H), 8.39 (s, 1H), 8.16 (s, 2H), 6.96 (s, 1H), 5.28 (s, 1H), 3.87 (m, 1H), 3.32 (s, 3H), 3.21 (s, 3H), 1.24 (d, J = 5.8 Hz, 3H).
13C NMR (151 MHz, DMSO-d6) δ 153.34, 150.32, 146.34, 144.30, 141.53, 139.01, 136.81, 136.18, 127.33, 126.24, 121.89, 95.71, 80.47, 76.58, 58.05, 56.95, 14.97.
MLT-748 does not show inhibitory activity on any of 22 other tested human proteases with IC50 values >100 μM
