Increasing the quality and robustness of biological and biomedical research using chemical probes

Increasing the quality and robustness of biological and biomedical research using chemical probes

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REVIEWS

Welcome to the Chemical Probes Portal, a free, public online resource providing expert reviews and guidance on chemical probes.

The Chemical Probes Portal supports the biological and biomedical research community in selecting the best chemical tools, such as inhibitors, activators and degraders, to use as chemical probes for their experiments. The Portal’s expert panel provides guidance on choosing the most suitable probe for in vitro and in vivo experiments, and shares best practice for application.

The Portal currently focuses on human proteins, but has plans to expand its coverage.

Cite us:

  • The Chemical Probes Portal – 2024: update on this public resource to support best-practice selection and use of small molecules in biomedical research, Sanfelice et al., Nucleic Acids Research 2025 gkae1062. DOI: 10.1093/nar/gkae1062
  • Please add our URL to your publication: www.chemicalprobes.org