Canertinib

Covalent Inhibitor of EGFR, ERBB2

Structure

Information

  • EGFR
  • ERBB2
  • Covalent Inhibitor
  • up to 1 uM

In Vitro Validations

Uniprot ID: P00533
Target Class: Kinase
Target SubClass: RTK
Potency: IC 50
Potency Value: 1.5 nM EGFR
Potency Assay: phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme
PDB ID for probe-target interaction (3D structure): --
Structure-activity relationship: yes
Target aliases:
Epidermal growth factor receptor, HER1, ERBB1, ERB ...

DOI Reference: 10.1021/jm990482t

In Cell Validations

In Vivo Data

I have extra information to add

SERP ratings and comments


No SERP comments found for Canertinib