1G244

1G244 : Inhibitor of DPP8, DPP9

Structure

SERP Rating

In Cells

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In Model Organisms

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Probe 1G244 is in the process of SERP review.

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Information

DPP8
DPP9

Inhibitor

up to 8 uM

More...

Probe Availability:

MedChemExpress

In Vitro Validations

Uniprot ID: Q6V1X1

Target Class: Peptidase

Target SubClass: Peptidase

Potency: IC 50

Potency Value: 14 nM

Potency Assay: Enzymatic assay

PDB ID for probe-target interaction (3D structure): 6TRX, 6EOR

Target aliases:

Dipeptidyl peptidase 8, DPRP1, DPP8, DPP8_HUMAN, D ...

DOI Reference: 10.1038/nchembio.2229

Uniprot ID: Q6V1X1

Target Class: Peptidase

Target SubClass: Peptidase

Potency: Ki

Potency Value: 0.9 nM DPP8

Potency Assay: Enzymatic assay

PDB ID for probe-target interaction (3D structure): --

Target aliases:

Dipeptidyl peptidase 8, DPRP1, DPP8, DPP8_HUMAN, D ...

DOI Reference: 10.1038/nchembio.2229

In Cell Validations

In Vivo Data

Off-Target Selectivity Assesments

Probe Selectivity in Vitro:

Selective over: DPP4 >100,000, FAP >100,000, DPP2 >100,000

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SERP ratings and comments

SERP Ratings

In Cell Rating

In Model Organisms

(last updated: 18 Mar 2024 )