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TP-021

TP-021 : Inhibitor of BCL6

Structure

Information

  • BCL6
  • Inhibitor
  • 1-10 uM

In Vitro Validations

Uniprot ID: P41182
Target Class: Transcription factor
Target SubClass: Transcriptional Repressor
Potency: IC50
Potency Value: 100 nM
Potency Assay: ELISA
PDB ID for probe-target interaction (3D structure): --
Target aliases:
B-cell lymphoma 6 protein, ZNF51, ZBTB27, LAZ3, BC ...

DOI Reference: 10.1016/j.bmc.2017.07.037

In Cell Validations

In Vivo Data

Off-Target Selectivity Assesments

Probe Selectivity in Vitro:
TP-021 and TP-021n show no significant inhibition at 1 μM in Takeda in house kinase panel (344 targets); Clean GPCR scan
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SERP ratings and comments

No SERP comments found for TP-021