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Sotuletinib

Sotuletinib : Inhibitor of CSF1R

Structure

Information

  • CSF1R
  • Inhibitor
  • up to 1 uM

In Vitro Validations

Uniprot ID: P07333
Target Class: Kinase
Target SubClass: TK
Potency: IC50
Potency Value: 1 nM
Potency Assay: Biochemical assay
PDB ID for probe-target interaction (3D structure): --
Target aliases:
Macrophage colony-stimulating factor 1 receptor, F ...

DOI Reference: 10.1038/nm.3337

In Cell Validations

In Vivo Data

Off-Target Selectivity Assesments

Potency assay (off target): Invitrogen Kinase profiling (30 kinases)shows a > 3000 fold selectivity against KIT
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