Ruxolitinib

Reagent Authentication Certificate: 
PDF icon Chemical Probes Portal Ruxolitinib.pdf
Protein target name: 
JAK1, JAK2
Mechanism of action: 
ATP-competitive inhibitor

Target Details

Target class: 
Protein kinase
Subclass: 
Tyrosine Kinase

Probe Details

Chemical Probes Portal ID: 
CPP78
Probe alias: 
941678-49-5, INCB-018424, INCB018424
SMILES string: 
C1CCC(C1)[C@@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
InChi Key: 
HFNKQEVNSGCOJV-OAHLLOKOSA-N
PAINs evaluation: 
PAINs free

Primary Reference