Imatinib

Protein target name: 
BCR-ABL, PDGFR, KIT
Mechanism of action: 
ATP-competitive inhibitor

Target Details

Target class: 
Protein kinase
Subclass: 
Tyrosine kinase
Target alias: 
BCR-ABL

Probe Details

Chemical Probes Portal ID: 
CPP72
Probe alias: 
STI571, CGP 57148
SMILES string: 
CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
InChi Key: 
KTUFNOKKBVMGRW-UHFFFAOYSA-N
PAINs evaluation: 
PAINs free

Primary Reference

External Resources