Fedratinib
Unsuitables - unsuitable to be used as a chemical probe
Structure
This is unsuitable as a chemical probe: While this
compound has been used to interrogate specific protein
targets, it is not a chemical probe and should not be used
in assays that depend on a potent and selective modulator
of the protein.
Non selective compound
Non selective compound: Intended target=JAK2; Number of targets=274; Wang et al., Evidence-based and quantitative prioritization of tool compounds in phenotypic drug discovery Cell Chem. Biol. 23, 862-874 (2016).