GI254023X

Inhibitor of ADAM10

Probe GI254023X is in the process of SERP review.

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Probe Availability:

Uniprot ID: O14672

Target Class: Other

Target SubClass: ADAM family

Potency: IC50

Potency Value: 5.3 nM

Potency Assay: Enzyme inhibition assay using fluorogenic substrate

PDB ID for probe-target interaction (3D structure): --

Target aliases:

Disintegrin and metalloproteinase domain-containin ...

Potency end-point : IC50

Probe Selectivity in Vitro:

100 fold selective over ADAM17 (541 nM):

Selectivity over other Recombinant MMPs 1 / 3 / 9 / 13 is 108 / 187 / 2.5 / 1.1 nM respectively.

No SERP comments found for GI254023X