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Browse Probes
Probe Name | Protein target | Target class | Subclass | Number of SAB Reviews |
Avg Rating (in cells)![]() |
---|---|---|---|---|---|
NI-57 | BRPF1, BRD1, BRPF3 | Epigenetics | Bromodomain | 0 | |
ICI-199441 | OPRK1 | GPCR | Opioid receptors | 0 | |
T0901317 | LXR-alpha, LXR-beta | Hormone pathway | Hormone receptor | 0 | |
T-26c | MMP13 | Protein metabolism | Metallopeptidase | 0 | |
Glyburide | ABCC8, KCNJ11 | Ion channel | Potassium channel | 0 | |
RO2468 | MDM2 | Other post-translational modification | E3 ubiquitin ligase | 0 | |
PFI-3 | SMARCA2, SMARCA4, PBRM1 | Epigenetics | Bromodomain | 0 | |
Repaglinide | ABCC8, KCNJ11 | Ion channel | Potassium channel | 0 | |
Eleutherobin | Tubulin | Structural protein | Cytoskeleton | 0 | |
TTT20171 | SDHC | Other | TCA cycle | 1 | |
Imatinib | BCR-ABL, PDGFR, KIT | Protein kinase | Tyrosine kinase | 3 | |
JW55 | TNKS, TNKS2 | Other post-translational modification | PARP | 3 | |
URMC-099 | MLK1, MLK2, MLK3 | Protein kinase | TKL | 3 | |
XAV939 | TNKS, TNKS2, PARP1, PARP2 | Other post-translational modification | PARP | 3 | |
UNC0638 | EHMT2, EHMT1 | Epigenetics | Protein methyltransferase | 2 | |
Cortistatin A | CDK8, CDK19 | Protein kinase | CMGC | 3 | |
BIX-01294 | EHMT2 | Epigenetics | Protein methyltransferase | 3 | |
TX1-85-1 | ERBB3 | Protein kinase | Tyrosine kinase | 3 | |
NI-42 | BRPF1, BRD1, BRPF3 | Epigenetics | Bromodomain | 3 | |
CFI-400945 | PLK4 | Protein kinase | Other | 3 | |
WH-4-023 | LCK, SRC | Protein kinase | Tyrosine Kinase | 5 | |
DS-437 | PRMT5, PRMT7 | Epigenetics | Protein methyltransferase | 3 | |
Englerin A | TRPC4, TRPC5 | Ion channel | Transient receptor potential channels | 3 | |
LLY-507 | SMYD2 | Epigenetics | Protein methyltransferase | 3 | |
AGI-6780 | IDH2 (R140Q mutant) | Other | Dehydrogenase | 3 | |
BMS-265246 | CDK, CDK2 | Protein kinase | CMGC | 3 | |
JQEZ5 | EZH2 | Epigenetics | Protein methyltransferase | 3 | |
PF-4800567 | CSNK1E | Protein kinase | CK1 | 3 | |
BI-D1870 | RPS6KA1, RPS6KA2, RPS6KA3, RPS6KA6 | Protein kinase | AGC | 3 | |
AGI-5198 | IDH1 (R132H mutant) | Other | Dehydrogenase | 3 | |
BI2536 | PLK1, PLK2, PLK3 | Protein kinase | Other | 3 | |
NMS-P118 | PARP1 | Other post-translational modification | PARP | 1 | |
KU-60019 | ATM | Protein kinase | Atypical | 2 | |
LP99 | BRD7, BRD9 | Epigenetics | Bromodomain | 3 | |
ABPA3 | UBA1, UBA3 | Other post-translational modification | E1 enzyme | 3 | |
BAY-299 | BRD1, TAF1, TAF1L | Epigenetics | Bromodomain | 3 | |
MIV-6R | KMT2A | Epigenetics | Protein methyltransferase | 3 | |
GPR40ant39 | FFAR1 | GPCR | Free fatty acid receptors | 3 | |
CX-4945 | CSNK2A1 | Protein kinase | CMGC | 3 | |
GSK-5959 | BRPF1 | Epigenetics | Bromodomain | 3 | |
GSK2801 | BAZ2A, BAZ2B | Epigenetics | Bromodomain | 3 | |
JAK3i | JAK3 | Protein kinase | Tyrosine kinase | 3 | |
RSL3 | GPX4 | Lipid metabolism | 3 | ||
CP-673451 | PDGFRbeta | Protein kinase | Tyrosine kinase | 3 | |
DDR1-IN-1 | DDR1 | Protein kinase | Tyrosine Kinase | 2 | |
L-Moses | PCAF, GCN5 | Epigenetics | Bromodomain | 6 | |
Cotransin | SEC61 complex | Integral membrane protein | General secrectory pathway | 2 | |
GNE-2861 | PAK4, PAK5, PAK6 | Protein kinase | STE20 | 2 | |
CPI-637 | CREBBP, EP300 | Epigenetics | Bromodomain | 2 | |
CPI-1205 | EZH2 | Epigenetics | Protein methyltransferase | 2 | |
Bistramide A | Actin | Structural protein | Cytoskeleton | 2 | |
STO609 | CAMKK1, CAMKK2 | Protein kinase | Other | 3 | |
XMD8-92 | MAPK7 | Protein kinase | CMGC | 3 | |
I-BET151 | BRD2, BRD3, BRD4 | Epigenetics | Bromodomain | 3 | |
VE-821 | ATR | Protein kinase | Atypical | 3 | |
MPS1-IN-1 | MPS1 | Protein kinase | Other | 3 | |
Afatinib | EGFR, ERBB2 | Protein kinase | Tyrosine Kinase | 3 | |
EPZ020411 | PRMT6 | Epigenetics | Protein methyltransferase | 3 | |
AZ0108 | PARP1, PARP2, PARP6 | Other post-translational modification | PARP | 3 | |
2-MT 63 | TEK | Protein kinase | Tyrosine kinase | 3 | |
UNC3866 | CBX7, CBX4 | Epigenetics | Methyl-lysine reader | 3 | |
A-1210477 | MCL1 | Other | BCL2 family | 3 | |
AVL-292 | BTK | Protein kinase | Tyrosine kinase | 3 | |
Bafetinib | BCR-ABL, LYN | Protein kinase | Tyrosine Kinase | 4 | |
GDC-0941 | PIK3CA, PIK3CD | Lipid kinase | Class I | 4 | |
eCF309 | MTOR | Protein kinase | Atypical | 3 | |
RGFP966 | HDAC3 | Epigenetics | HDAC | 3 | |
HG-9-91-01 | SIK1, SIK2, SIK3 | Protein kinase | CAMK | 3 | |
Olaparib | PARPs | Other post-translational modification | PARP | 3 | |
BIX-02188 | MAP2K5 | Protein kinase | STE | 3 | |
BMX-IN-1 | BMX | Protein kinase | Tyrosine kinase | 3 | |
RG7112 | MDM2 | Other post-translational modification | E3 ubiquitin ligase | 2 | |
E7449 | PARP1, PARP2, TNKS, TNKS2 | Other post-translational modification | PARP | 3 | |
KH-CB19 | CLK1, CLK4, DYRK1A | Protein kinase | CMGC | 3 | |
GSK-J4 | KDM6A, KDM6B | Epigenetics | Lysine demethylase | 2 | |
GSK864 | IDH1 (mutant) | Other | Dehydrogenase | 2 | |
I-BRD9 | BRD9 | Epigenetics | Bromodomain | 3 | |
AZ6102 | TNKS, TNKS2 | Other post-translational modification | PARP | 3 | |
MI-888 | MDM2 | Other post-translational modification | E3 ubiquitin ligase | 3 | |
PF-3758309 | PAK1, PAK4, PAK5, PAK6 | Protein kinase | STE | 3 | |
ACY-738 | HDAC6 | Epigenetics | HDAC | 3 | |
A-1155463 | BCLXL | Other | BCL2 family | 3 | |
GNE7915 | LRRK2 | Protein kinase | TKL | 3 | |
Salvinorin A | OPRK1 | GPCR | Opioid receptor | 3 | |
UNC2025 | MERTK, FLT3 | Protein kinase | Tyrosine kinase | 3 | |
Pevonedistat | NEDD8-activating enzyme | Other post-translational modification | Ubiquitin like modifier activating enzymes | 3 | |
KI-696 | KEAP1 | Other post-translational modification | Protein ubiquitination | 2 | |
BI-9564 | BRD9, BRD7 | Epigenetics | Bromodomain | 3 | |
BAZ2-ICR | BAZ2A, BAZ2B | Epigenetics | Bromodomain | 3 | |
GW3965 | LXR-alpha, LXR-beta | Hormone pathway | Hormone receptor | 3 | |
AZ191 | DYRK1B | Protein kinase | CMGC | 3 | |
eCF506 | SRC | Protein kinase | Tyrosine kinase | 4 | |
WZ4003 | NUAK1, NUAK2 | Protein kinase | CAMK | 3 | |
I-CBP112 | CREBBP, EP300 | Epigenetics | Bromodomain | 3 | |
AMG-18 | ERN1 | Protein kinase | Other | 3 | |
EPZ-6438 | EZH2 | Epigenetics | Protein Methyltransferase | 3 | |
GSK591 | PRMT5 | Epigenetics | Protein methyltransferase | 3 | |
ML323 | USP1, WDR48 | Other post-translational modification | Deubiquitinase | 3 | |
NVP-AEW541 | IGF1R | Protein kinase | Tyrosine Kinase | 3 | |
Filgotinib | JAK1 | Protein kinase | Tyrosine kinase | 3 | |
PDD00017273 | PARG | DNA replication & repair enzyme | 3 | ||
THZ1 | CDK7 | Protein kinase | CMGC | 3 | |
CCT244747 | CHEK1 | Protein kinase | CAMK | 3 | |
Selumetinib | MAP2K1 | Protein kinase | STE | 3 | |
BiBET | BRD4, BRD3, BRD2, BRDT | Epigenetics | Bromodomain | 3 | |
AC220 | FLT3 | Protein kinase | Tyrosine Kinase | 3 | |
SGC-CBP30 | CREBBP, EP300 | Epigenetics | Bromodomain | 3 | |
PF3644022 | MAPKAPK2 | Protein kinase | CAMK | 3 | |
JNK-IN-8 | MAPK8, MAPK9, MAPK10 | Protein kinase | CMGC | 3 | |
Rapamycin | MTOR | Protein kinase | Atypical | 3 | |
Tubacin | HDAC6 | Epigenetics | HDAC | 3 | |
Talazoparib | PARPs | Other post-translational modification | PARP | 3 | |
WEHI-539 | BCLXL | Other | BCL2 family | 2 | |
MZ1 | BRD4 | Epigenetics | Bromodomain | 4 | |
GNF-5 | BCR-ABL | Protein kinase | Tyrosine kinase | 2 | |
UNC1999 | EZH1, EZH2 | Epigenetics | Protein methyltransferase | 2 | |
GSK583 | RIPK2 | Protein kinase | AGC | 3 | |
PF-CBP1 | CREBBP | Epigenetics | Bromodomain | 3 | |
Tofacitinib | JAK1, JAK2, JAK3 | Protein kinase | Tyrosine Kinase | 3 | |
EPZ-5676 | DOT1L | Epigenetics | Protein methyltransferase | 3 | |
A-395 | EED | Epigenetics | Polycomb family | 3 | |
P505-15 | SYK | Protein kinase | Tyrosine Kinase | 3 | |
BMS-911543 | JAK2 | Protein kinase | Tyrosine kinase | 3 | |
CHIR-99021 | GSK3A, GSK3B | Protein kinase | CMGC | 3 | |
NVS-PAK1-1 | PAK1 | Protein kinase | STE | 3 | |
SGX-523 | MET | Protein kinase | Tyrosine Kinase | 3 | |
AMG900 | AURKA, AURKB, AURKC | Protein kinase | Other | 3 | |
BLU9931 | FGFR4 | Protein kinase | Tyrosine kinase | 3 | |
Romidepsin | HDAC1, HDAC2, HDAC3, HDAC8 | Epigenetics | HDAC | 3 | |
EPZ011989 | EZH1, EZH2 | Epigenetics | Protein methyltransferase | 3 | |
CCT241533 | CHEK2 | Protein kinase | CAMK | 3 | |
Skepinone-L | MAPK14 | Protein kinase | 3 | ||
GDC-0879 | BRAF V600E | Protein kinase | TKL | 3 | |
AZD1152 | AURKB | Protein kinase | Other | 3 | |
KZR-504 | PSMB9 | Protein metabolism | Proteasome subunit | 3 | |
VH298 | VHL | Other post-translational modification | E3 ubiquitin ligase | 3 | |
BGJ-398 | FGFR1, FGFR2, FGFR3, FGFR4 | Protein kinase | Tyrosine Kinase | 3 | |
EI1 | EZH2 | Epigenetics | Protein methyltransferase | 3 | |
G-5555 | PAK1, PAK2, PAK3 | Protein kinase | STE | 3 | |
PF-477736 | CHEK1 | Protein kinase | CAMK | 3 | |
AZD2014 | MTOR | Protein kinase | Atypical | 3 | |
GSK484 | PADI4 | Epigenetics | Arginine deaminase | 3 | |
SGC707 | PRMT3 | Epigenetics | Protein methyltransferase | 4 | |
SGC0946 | DOT1L | Epigenetics | Protein methyltransferase | 4 | |
EED226 | EED | Epigenetics | Polycomb family | 4 | |
GSK4027 | PCAF, GCN5 | Epigenetics | Bromodomain | 5 | |
VX-745 | MAPK14 | Protein kinase | CMGC | 3 | |
RO5353 | MDM2 | Other post-translational modification | E3 ubiquitin ligase | 2 | |
MS023 | PRMT1, PRMT3, PRMT4, PRMT6, PRMT8 | Epigenetics | Protein methyltransferase | 3 | |
CPI-0610 | BRD2, BRD3, BRD4, BRDT | Epigenetics | Bromodomain | 3 | |
Ruxolitinib | JAK1, JAK2 | Protein kinase | Tyrosine Kinase | 3 | |
GSK343 | EZH2 | Epigenetics | Protein methyltransferase | 3 | |
A-366 | EHMT2, EHMT1 | Epigenetics | Protein methyltransferase | 3 | |
Linsitinib | IGF1R, INSR, INSRR | Protein kinase | Tyrosine kinase | 1 | |
CP-724714 | ERBB2 | Protein kinase | Tyrosine kinase | 3 | |
MK-5108 | AURKA | Protein kinase | Other | 3 | |
CPI-360 | EZH2 | Epigenetics | Protein methyltransferase | 2 | |
S63845 | MCL1 | Other | BCL2 family | 2 | |
(R)-PFI-2 | SETD7 | Epigenetics | Protein methyltransferase | 3 | |
AM-6761 | MDM2 | Other post-translational modification | E3 ubiquitin ligase | 3 | |
Niraparib | PARP1, PARP2 | Other post-translational modification | PARP | 3 | |
CCT251236 | PIR | Other | Cupin | 2 | |
GSK481 | RIPK1 | Protein kinase | TKL | 3 | |
CCT251545 | CDK8, CDK19 | Protein kinase | CMGC | 3 | |
BAY-598 | SMYD2 | Epigenetics | Protein methyltransferase | 3 | |
SCH772984 | MAPK1, MAPK3 | Protein kinase | CMGC | 3 | |
EPZ015666 | PRMT5 | Epigenetics | Protein methyltransferase | 3 | |
Veliparib | PARP1, PARP2 | Other post-translational modification | PARP | 3 | |
Venetoclax | BCL2 | Other | 2 | ||
GSK2334470 | PDK1 | Protein kinase | AGC | 3 | |
RG7388 | MDM2 | Other post-translational modification | E3 ubiquitin ligase | 2 | |
A-196 | KMT5B, KMT5C | Epigenetics | Protein methyltransferase | 3 | |
Taxol | Beta-Tubulin | Structural protein | Cytoskeleton | 1 | |
AX15836 | MAPK7 | Protein kinase | CMGC | 3 | |
CPI-169 | EZH1, EZH2 | Epigenetics | Protein methyltransferase | 3 | |
MT1 | BRD2, BRD3, BRD4, BRDT | Epigenetics | Bromodomain | 3 | |
CGI1746 | BTK | Protein kinase | Tyrosine kinase | 3 | |
OICR-9429 | WDR5 | Structural protein | WD40-repeat proteins | 3 | |
EPZ004777 | DOT1L | Epigenetics | Protein Methyltransferase | 3 | |
UNC0642 | EHMT2, EHMT1 | Epigenetics | Protein methyltransferase | 3 | |
PD0332991 | CDK4, CDK6 | Protein kinase | CMGC | 3 | |
BYL-719 | PIK3CA | Lipid kinase | Class I | 3 | |
CH5424802 | ALK | Protein kinase | Tyrosine kinase | 3 | |
JQ1 | BRD2, BRD3, BRD4, BRDT | Epigenetics | Bromodomain | 3 | |
FM-381 | JAK3 | Protein kinase | Tyrosine kinase | 3 | |
UNC1215 | L3MBTL3 | Epigenetics | Malignant brain tumor Reader | 3 | |
AMG232 | MDM2 | Other post-translational modification | E3 ubiquitin ligase | 2 | |
PFI-1 | BRD2, BRD3, BRD4, BRDT | Epigenetics | Bromodomain | 3 |