Browse Probes

Probe Name Protein target Target class Subclass Number of SAB Reviews Avg Rating (in cells)sort descending
PFI-3 SMARCA2, SMARCA4, PBRM1 Epigenetics Bromodomain 0
Repaglinide ABCC8, KCNJ11 Ion channel Potassium channel 0
Eleutherobin Tubulin Structural protein Cytoskeleton 0
NI-57 BRPF1, BRD1, BRPF3 Epigenetics Bromodomain 0
9-ME-1 BRD2, BRD3, BRD4, BRDT Epigenetics Bromodomain 0
RO2468 MDM2 Other post-translational modification E3 ubiquitin ligase 0
ICI-199441 OPRK1 GPCR Opioid receptors 0
CM11 VHL Other 0
T0901317 LXR-alpha, LXR-beta Hormone pathway Hormone receptor 0
T-26c MMP13 Protein metabolism Metallopeptidase 0
Glyburide ABCC8, KCNJ11 Ion channel Potassium channel 0
AT1 Brd4 Epigenetics Bromodomain 0
TTT20171 SDHC Other TCA cycle 1
1.0000
Imatinib BCR-ABL, PDGFR, KIT Protein kinase Tyrosine kinase 3
1.0000
JW55 TNKS, TNKS2 Other post-translational modification PARP 3
1.0000
XAV939 TNKS, TNKS2, PARP1, PARP2 Other post-translational modification PARP 3
1.3333
URMC-099 MLK1, MLK2, MLK3 Protein kinase TKL 3
1.3333
UNC0638 EHMT2, EHMT1 Epigenetics Protein methyltransferase 2
1.5000
Cortistatin A CDK8, CDK19 Protein kinase CMGC 3
1.6667
BIX-01294 EHMT2 Epigenetics Protein methyltransferase 3
1.6667
TX1-85-1 ERBB3 Protein kinase Tyrosine kinase 3
1.6667
NI-42 BRPF1, BRD1, BRPF3 Epigenetics Bromodomain 3
1.6667
CFI-400945 PLK4 Protein kinase Other 3
1.6667
WH-4-023 LCK, SRC Protein kinase Tyrosine Kinase 5
1.8000
LLY-507 SMYD2 Epigenetics Protein methyltransferase 3
2.0000
ABPA3 UBA1, UBA3 Other post-translational modification E1 enzyme 3
2.0000
DS-437 PRMT5, PRMT7 Epigenetics Protein methyltransferase 3
2.0000
Englerin A TRPC4, TRPC5 Ion channel Transient receptor potential channels 3
2.0000
NMS-P118 PARP1 Other post-translational modification PARP 1
2.0000
AGI-6780 IDH2 (R140Q mutant) Other Dehydrogenase 3
2.0000
BMS-265246 CDK, CDK2 Protein kinase CMGC 3
2.0000
JQEZ5 EZH2 Epigenetics Protein methyltransferase 3
2.0000
PF-4800567 CSNK1E Protein kinase CK1 3
2.0000
BI2536 PLK1, PLK2, PLK3 Protein kinase Other 3
2.0000
BI-D1870 RPS6KA1, RPS6KA2, RPS6KA3, RPS6KA6 Protein kinase AGC 3
2.0000
AGI-5198 IDH1 (R132H mutant) Other Dehydrogenase 3
2.0000
KU-60019 ATM Protein kinase Atypical 2
2.0000
LP99 BRD7, BRD9 Epigenetics Bromodomain 3
2.0000
CP-673451 PDGFRbeta Protein kinase Tyrosine kinase 3
2.3333
BAY-299 BRD1, TAF1, TAF1L Epigenetics Bromodomain 3
2.3333
MIV-6R KMT2A Epigenetics Protein methyltransferase 3
2.3333
GPR40ant39 FFAR1 GPCR Free fatty acid receptors 3
2.3333
GSK2801 BAZ2A, BAZ2B Epigenetics Bromodomain 3
2.3333
CX-4945 CSNK2A1 Protein kinase CMGC 3
2.3333
GSK-5959 BRPF1 Epigenetics Bromodomain 3
2.3333
JAK3i JAK3 Protein kinase Tyrosine kinase 3
2.3333
RSL3 GPX4 Lipid metabolism 3
2.3333
Bistramide A Actin Structural protein Cytoskeleton 2
2.5000
DDR1-IN-1 DDR1 Protein kinase Tyrosine Kinase 2
2.5000
L-Moses PCAF, GCN5 Epigenetics Bromodomain 6
2.5000
Cotransin SEC61 complex Integral membrane protein General secrectory pathway 2
2.5000
GNE-2861 PAK4, PAK5, PAK6 Protein kinase STE20 2
2.5000
CPI-637 CREBBP, EP300 Epigenetics Bromodomain 2
2.5000
CPI-1205 EZH2 Epigenetics Protein methyltransferase 2
2.5000
UNC3866 CBX7, CBX4 Epigenetics Methyl-lysine reader 3
2.6667
A-1210477 MCL1 Other BCL2 family 3
2.6667
AVL-292 BTK Protein kinase Tyrosine kinase 3
2.6667
STO609 CAMKK1, CAMKK2 Protein kinase Other 3
2.6667
XMD8-92 MAPK7 Protein kinase CMGC 3
2.6667
I-BET151 BRD2, BRD3, BRD4 Epigenetics Bromodomain 3
2.6667
VE-821 ATR Protein kinase Atypical 3
2.6667
EPZ020411 PRMT6 Epigenetics Protein methyltransferase 3
2.6667
Afatinib EGFR, ERBB2 Protein kinase Tyrosine Kinase 3
2.6667
MPS1-IN-1 MPS1 Protein kinase Other 3
2.6667
AZ0108 PARP1, PARP2, PARP6 Other post-translational modification PARP 3
2.6667
2-MT 63 TEK Protein kinase Tyrosine kinase 3
2.6667
Bafetinib BCR-ABL, LYN Protein kinase Tyrosine Kinase 4
2.7500
GDC-0941 PIK3CA, PIK3CD Lipid kinase Class I 4
2.7500
GW3965 LXR-alpha, LXR-beta Hormone pathway Hormone receptor 3
3.0000
AZ191 DYRK1B Protein kinase CMGC 3
3.0000
KI-696 KEAP1 Other post-translational modification Protein ubiquitination 2
3.0000
BI-9564 BRD9, BRD7 Epigenetics Bromodomain 3
3.0000
MI-888 MDM2 Other post-translational modification E3 ubiquitin ligase 3
3.0000
BIX-02188 MAP2K5 Protein kinase STE 3
3.0000
eCF506 SRC Protein kinase Tyrosine kinase 4
3.0000
HG-9-91-01 SIK1, SIK2, SIK3 Protein kinase CAMK 3
3.0000
RGFP966 HDAC3 Epigenetics HDAC 3
3.0000
eCF309 MTOR Protein kinase Atypical 3
3.0000
Olaparib PARPs Other post-translational modification PARP 3
3.0000
I-BRD9 BRD9 Epigenetics Bromodomain 3
3.0000
BMX-IN-1 BMX Protein kinase Tyrosine kinase 3
3.0000
RG7112 MDM2 Other post-translational modification E3 ubiquitin ligase 2
3.0000
E7449 PARP1, PARP2, TNKS, TNKS2 Other post-translational modification PARP 3
3.0000
PF-3758309 PAK1, PAK4, PAK5, PAK6 Protein kinase STE 3
3.0000
KH-CB19 CLK1, CLK4, DYRK1A Protein kinase CMGC 3
3.0000
GSK-J4 KDM6A, KDM6B Epigenetics Lysine demethylase 2
3.0000
GSK864 IDH1 (mutant) Other Dehydrogenase 2
3.0000
AZ6102 TNKS, TNKS2 Other post-translational modification PARP 3
3.0000
Salvinorin A OPRK1 GPCR Opioid receptor 3
3.0000
GNE7915 LRRK2 Protein kinase TKL 3
3.0000
ACY-738 HDAC6 Epigenetics HDAC 3
3.0000
A-1155463 BCLXL Other BCL2 family 3
3.0000
BAZ2-ICR BAZ2A, BAZ2B Epigenetics Bromodomain 3
3.0000
UNC2025 MERTK, FLT3 Protein kinase Tyrosine kinase 3
3.0000
WZ4003 NUAK1, NUAK2 Protein kinase CAMK 3
3.0000
I-CBP112 CREBBP, EP300 Epigenetics Bromodomain 3
3.0000
Pevonedistat NEDD8-activating enzyme Other post-translational modification Ubiquitin like modifier activating enzymes 3
3.0000
Tubacin HDAC6 Epigenetics HDAC 3
3.3333
Talazoparib PARPs Other post-translational modification PARP 3
3.3333
NVP-AEW541 IGF1R Protein kinase Tyrosine Kinase 3
3.3333
AMG-18 ERN1 Protein kinase Other 3
3.3333
EPZ-6438 EZH2 Epigenetics Protein Methyltransferase 3
3.3333
GSK591 PRMT5 Epigenetics Protein methyltransferase 3
3.3333
THZ1 CDK7 Protein kinase CMGC 3
3.3333
ML323 USP1, WDR48 Other post-translational modification Deubiquitinase 3
3.3333
Filgotinib JAK1 Protein kinase Tyrosine kinase 3
3.3333
PDD00017273 PARG DNA replication & repair enzyme 3
3.3333
Selumetinib MAP2K1 Protein kinase STE 3
3.3333
SGC-CBP30 CREBBP, EP300 Epigenetics Bromodomain 3
3.3333
CCT244747 CHEK1 Protein kinase CAMK 3
3.3333
BiBET BRD4, BRD3, BRD2, BRDT Epigenetics Bromodomain 3
3.3333
Rapamycin MTOR Protein kinase Atypical 3
3.3333
PF3644022 MAPKAPK2 Protein kinase CAMK 3
3.3333
JNK-IN-8 MAPK8, MAPK9, MAPK10 Protein kinase CMGC 3
3.3333
AC220 FLT3 Protein kinase Tyrosine Kinase 3
3.3333
WEHI-539 BCLXL Other BCL2 family 2
3.5000
MZ1 BRD4 Epigenetics Bromodomain 4
3.5000
GNF-5 BCR-ABL Protein kinase Tyrosine kinase 2
3.5000
UNC1999 EZH1, EZH2 Epigenetics Protein methyltransferase 2
3.5000
BGJ-398 FGFR1, FGFR2, FGFR3, FGFR4 Protein kinase Tyrosine Kinase 3
3.6667
G-5555 PAK1, PAK2, PAK3 Protein kinase STE 3
3.6667
EI1 EZH2 Epigenetics Protein methyltransferase 3
3.6667
Tofacitinib JAK1, JAK2, JAK3 Protein kinase Tyrosine Kinase 3
3.6667
EPZ-5676 DOT1L Epigenetics Protein methyltransferase 3
3.6667
PF-477736 CHEK1 Protein kinase CAMK 3
3.6667
AZD2014 MTOR Protein kinase Atypical 3
3.6667
GSK484 PADI4 Epigenetics Arginine deaminase 3
3.6667
CHIR-99021 GSK3A, GSK3B Protein kinase CMGC 3
3.6667
GSK583 RIPK2 Protein kinase AGC 3
3.6667
P505-15 SYK Protein kinase Tyrosine Kinase 3
3.6667
PF-CBP1 CREBBP Epigenetics Bromodomain 3
3.6667
A-395 EED Epigenetics Polycomb family 3
3.6667
SGX-523 MET Protein kinase Tyrosine Kinase 3
3.6667
BMS-911543 JAK2 Protein kinase Tyrosine kinase 3
3.6667
NVS-PAK1-1 PAK1 Protein kinase STE 3
3.6667
CCT241533 CHEK2 Protein kinase CAMK 3
3.6667
EPZ011989 EZH1, EZH2 Epigenetics Protein methyltransferase 3
3.6667
AMG900 AURKA, AURKB, AURKC Protein kinase Other 3
3.6667
BLU9931 FGFR4 Protein kinase Tyrosine kinase 3
3.6667
Romidepsin HDAC1, HDAC2, HDAC3, HDAC8 Epigenetics HDAC 3
3.6667
Skepinone-L MAPK14 Protein kinase 3
3.6667
GDC-0879 BRAF V600E Protein kinase TKL 3
3.6667
AZD1152 AURKB Protein kinase Other 3
3.6667
KZR-504 PSMB9 Protein metabolism Proteasome subunit 3
3.6667
VH298 VHL Other post-translational modification E3 ubiquitin ligase 3
3.6667
SGC707 PRMT3 Epigenetics Protein methyltransferase 4
3.7500
SGC0946 DOT1L Epigenetics Protein methyltransferase 4
3.7500
EED226 EED Epigenetics Polycomb family 4
3.7500
GSK4027 PCAF, GCN5 Epigenetics Bromodomain 5
3.8000
PD0332991 CDK4, CDK6 Protein kinase CMGC 3
4.0000
CH5424802 ALK Protein kinase Tyrosine kinase 3
4.0000
MS023 PRMT1, PRMT3, PRMT4, PRMT6, PRMT8 Epigenetics Protein methyltransferase 3
4.0000
FM-381 JAK3 Protein kinase Tyrosine kinase 3
4.0000
MI-77301 MDM2 Other post-translational modification E3 ubiquitin ligase 3
4.0000
Ruxolitinib JAK1, JAK2 Protein kinase Tyrosine Kinase 3
4.0000
GSK343 EZH2 Epigenetics Protein methyltransferase 3
4.0000
A-366 EHMT2, EHMT1 Epigenetics Protein methyltransferase 3
4.0000
VX-745 MAPK14 Protein kinase CMGC 3
4.0000
(R)-PFI-2 SETD7 Epigenetics Protein methyltransferase 3
4.0000
CPI-0610 BRD2, BRD3, BRD4, BRDT Epigenetics Bromodomain 3
4.0000
MK-5108 AURKA Protein kinase Other 3
4.0000
CP-724714 ERBB2 Protein kinase Tyrosine kinase 3
4.0000
CPI-360 EZH2 Epigenetics Protein methyltransferase 2
4.0000
BAY-598 SMYD2 Epigenetics Protein methyltransferase 3
4.0000
Niraparib PARP1, PARP2 Other post-translational modification PARP 3
4.0000
S63845 MCL1 Other BCL2 family 2
4.0000
AMG232 MDM2 Other post-translational modification E3 ubiquitin ligase 2
4.0000
CCT251236 PIR Other Cupin 2
4.0000
GSK2334470 PDK1 Protein kinase AGC 3
4.0000
GSK481 RIPK1 Protein kinase TKL 3
4.0000
A-196 KMT5B, KMT5C Epigenetics Protein methyltransferase 3
4.0000
CCT251545 CDK8, CDK19 Protein kinase CMGC 3
4.0000
SCH772984 MAPK1, MAPK3 Protein kinase CMGC 3
4.0000
EPZ015666 PRMT5 Epigenetics Protein methyltransferase 3
4.0000
RO5353 MDM2 Other post-translational modification E3 ubiquitin ligase 2
4.0000
Veliparib PARP1, PARP2 Other post-translational modification PARP 3
4.0000
OICR-9429 WDR5 Structural protein WD40-repeat proteins 3
4.0000
Venetoclax BCL2 Other 2
4.0000
RG7388 MDM2 Other post-translational modification E3 ubiquitin ligase 2
4.0000
Linsitinib IGF1R, INSR, INSRR Protein kinase Tyrosine kinase 1
4.0000
BYL-719 PIK3CA Lipid kinase Class I 3
4.0000
AX15836 MAPK7 Protein kinase CMGC 3
4.0000
JQ1 BRD2, BRD3, BRD4, BRDT Epigenetics Bromodomain 3
4.0000
CPI-169 EZH1, EZH2 Epigenetics Protein methyltransferase 3
4.0000
MT1 BRD2, BRD3, BRD4, BRDT Epigenetics Bromodomain 3
4.0000
EPZ004777 DOT1L Epigenetics Protein Methyltransferase 3
4.0000
AM-6761 MDM2 Other post-translational modification E3 ubiquitin ligase 3
4.0000
CGI1746 BTK Protein kinase Tyrosine kinase 3
4.0000
PFI-1 BRD2, BRD3, BRD4, BRDT Epigenetics Bromodomain 3
4.0000
UNC0642 EHMT2, EHMT1 Epigenetics Protein methyltransferase 3
4.0000
UNC1215 L3MBTL3 Epigenetics Malignant brain tumor Reader 3
4.0000